Columbus, United States: innovation profile

Columbus is number 59 in the 311 Innovation Cities Index, with an innovation score of 71. It is home to 6 R&D labs, 15 startups, 11 investors and 14 of the world's largest companies in the 311 Institute directories.

Part of the 311 Innovation Cities Index. Last updated 7 October 2026.

Largest companies

• Cummins Inc. (#240)
• American Electric Power Co Inc. (#374)
• Battelle Memorial Institute (#585)
• Bath & Body Works, Inc. (#952)
• M/I Homes (#1384)
• Mettler Toledo (#1461)
• Worthington Steel, Inc. (#1613)
• Installed Building Products, Inc. (#1779)
• Designer Brands Inc. (#1812)
• Worthington Industries (#2662)
• Aflac Incorporated (#F96)
• Huntington Bancshares (#F135)
• Alliance Data (#F231)
• Root, Inc. (#F313)

Startups

• Acculon Energy
• AndHealth
• Arrellio
• Clarametyx Biosciences
• Clarence Health
• Healia
• Helm Health
• Homage Holdings
• HubiFi
• MemryHealth
• Myoptechs
• Power To Hydrogen
• Prescribe FIT
• Redi.Health
• TegoSens

Investors

• Drive Capital
• Grandview Partners
• Gryphon Financial Partners
• Heartland Group Holdings
• NCT Fund Management
• R1 Capital
• Rockbridge Capital
• Stonehenge Partners
• SWS Partners
• Trinity Financial
• Watermark Investment

R&D labs

Battelle, Cardinal Health, Hyper Tech Research (United States), Ohio Educational Technology Conference, Ohio Supercomputer Center, The Ohio State University.