Knoxville, United States: innovation profile

Knoxville is number 586 in the 311 Innovation Cities Index, with an innovation score of 8. It is home to 1 R&D lab, 5 startups and 1 investor in the 311 Institute directories.

Part of the 311 Innovation Cities Index (311institute.com). Last updated 7 October 2026.

Startups

• Aro Technology
• Emory Investor II
• Orthoforum Value Network
• TitanX Holdings
• VMC Mar Com

Investors

• GSV Equity Holdings

R&D labs

National Transportation Research Center.