Charleston, United States: innovation profile

Charleston is number 221 in the 311 Innovation Cities Index, with an innovation score of 23. It is home to 2 R&D labs, 3 startups, 7 investors and 2 of the world's largest companies in the 311 Institute directories.

Part of the 311 Innovation Cities Index (311institute.com). Last updated 7 October 2026.

Largest companies

• Blackbaud (#2907)
• United Bankshares Inc. (#F304)

Startups

• Further Technology Holdings
• Scout OS
• Secro

Investors

• Bowside Capital
• Frontline Healthcare Partners
• Global Frontier Investments
• Greystar Investment Group
• Ivy Evergreen
• Liberty Hall Capital Partners
• Permcap Investment Office

R&D labs

Naval Information Warfare Systems Command, NCCOS Hollings Marine Laboratory.