Jacksonville, United States: innovation profile

Jacksonville is number 219 in the 311 Innovation Cities Index, with an innovation score of 23. It is home to 1 R&D lab, 6 startups, 1 investor and 7 of the world's largest companies in the 311 Institute directories.

Part of the 311 Innovation Cities Index (311institute.com). Last updated 7 October 2026.

Largest companies

• CSX Corporation (#558)
• Fidelity National Information Services, Inc. (#716)
• Landstar System, Inc. (#1332)
• Dream Finders Homes, Inc. (#1398)
• Regency Centers (#2484)
• Rayonier Advanced Materials Inc. (#2561)
• Fidelity National Financial, Inc. (#F108)

Startups

• Adas AI Trak
• Azimuth GRC
• Medical Microinstruments
• Star Catcher Industries
• TendedBar
• Voxeq

Investors

• Brinkmere Capital

R&D labs

Jacksonville Center for Clinical Research.