Lexington, United States: innovation profile

Lexington is number 281 in the 311 Innovation Cities Index, with an innovation score of 18. It is home to 3 R&D labs, 9 startups, 1 investor and 2 of the world's largest companies in the 311 Institute directories.

Part of the 311 Innovation Cities Index (311institute.com). Last updated 7 October 2026.

Largest companies

• Somnigroup International Inc. (#932)
• Valvoline (#2360)

Startups

• Alzheon
• Amplifyer Bio
• Avana Health
• BGA Site Services
• Data Management & Compliance, Inc. DBA Warchest
• ElectroWire
• PowerTech Water
• Ray Fitness Systems
• VulnCheck

Investors

• Middleground Capital

R&D labs

Atmospheric and Environmental Research, Boston Collaborative Drug Surveillance Program, US Department of Defense.