Sheffield, United Kingdom: innovation profile

Sheffield is number 573 in the 311 Innovation Cities Index, with an innovation score of 8. It is home to 2 R&D labs, 4 startups and 1 of the world's largest companies in the 311 Institute directories.

Part of the 311 Innovation Cities Index (311institute.com). Last updated 7 October 2026.

Largest companies

• Sig plc (#1624)

Startups

• Aegiq
• Crucible Therapeutics
• Evolutor
• Phlux Technology

R&D labs

Leverhulme Trust, University of Sheffield.